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JP Labs · Metabolic Research · Research Peptide

GLP2-T (Dual Agonist)

Dual GIP/GLP-1 receptor agonist. Two complementary incretin pathways in a single compound — available in 10mg and 20mg.

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About GLP2-T

GLP2-T is the research designation for GLP2-T, a dual receptor agonist that targets both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors simultaneously. By engaging two distinct incretin pathways, it represents a mechanistic evolution from single-receptor GLP-1 agonists.

GIP receptor activation influences insulin secretion in a glucose-dependent manner and may modulate adipose tissue function and energy balance. GLP-1 receptor activation reduces gastric emptying, suppresses glucagon secretion, and decreases appetite signaling through central and peripheral mechanisms. The dual agonism creates complementary and potentially synergistic effects that have made GLP2-T a subject of significant research interest in metabolic science.

📚 Go Deeper
Not sure whether GLP2-T or GLP3-R fits your research design? See our side-by-side GLP3-R vs GLP2-T comparison guide. For more on how single, dual, and triple receptor agonists compare, read our GLP receptor agonist guide.
Purity
≥99%
HPLC-UV verified
Identity
LC-MS Confirmed
Mass spectrometry
Form
Lyophilized Powder
Requires reconstitution
Storage
Lyophilized: Room temp or 2–8°C
After reconstitution: 2–8°C
Available Sizes
10mg
Lyophilized powder · 99%+ purity
$60
20mg
Lyophilized powder · 99%+ purity
$75
🧪 Reconstitution
Reconstitute with Bacteriostatic Water. GLP2-T is particularly prone to foaming — add BAC Water very slowly angled down the vial wall. Do not shake. Swirl gently. Standard protocol: 1 mL BAC Water per 10mg vial (10 mg/mL); 2 mL per 20mg vial (10 mg/mL). If foaming occurs, allow the vial to rest refrigerated for 10–15 minutes before use. Visit our full Reconstitution Guide and Dosing Calculator for detailed instructions. For a complete reference on storage temperatures, light sensitivity, and shelf life across compound types, see our Peptide Storage 101 guide.

Research Applications

GLP2-T is used in research investigating dual incretin receptor pathway modulation, insulin sensitivity, appetite regulation, and body composition. Research applications include comparative studies between mono- and dual-receptor agonists, investigations of GIP vs. GLP-1 contribution to metabolic outcomes, and studies of gastric motility under dual-receptor conditions.

For research use only. All products sold by JP Labs are intended strictly for in vitro laboratory research. Not for human or veterinary use. Not FDA approved for any therapeutic purpose.

Common Questions

What is GLP2-T?
GLP2-T is the research name for GLP2-T — a dual GIP/GLP-1 receptor agonist. It differs from GLP-1 monoagonists by additionally targeting the GIP receptor, which adds a second incretin pathway to the mechanism.
What sizes is GLP2-T available in?
JP Labs carries GLP2-T in 10mg and 20mg vials.
How do I reconstitute GLP2-T?
Use Bacteriostatic Water. GLP2-T is prone to foaming — add BAC Water very slowly down the vial wall. For 10mg: add 1 mL BAC Water (10 mg/mL). For 20mg: add 2 mL BAC Water (10 mg/mL). Swirl gently, never shake. If foaming occurs, rest in refrigerator 10–15 minutes.
What is the difference between GLP2-T and GLP3-R?
GLP2-T targets two receptors: GIP and GLP-1. GLP3-R targets three: GIP, GLP-1, and glucagon. The additional glucagon receptor component in GLP3-R is believed to further increase energy expenditure.
Is GLP2-T the same as semaglutide?
No. Semaglutide is a GLP-1 monoagonist — it targets only the GLP-1 receptor. GLP2-T targets both GIP and GLP-1 receptors, making it mechanistically distinct.

Related Compounds

Regulatory Notice

None of the statements on this website have been reviewed or approved by the U.S. Food and Drug Administration. JP Labs products are not intended to diagnose, treat, cure, or prevent any disease or medical condition. All products are sold strictly for in vitro laboratory research purposes. They are not for human or animal use of any kind. DiPerna Services, LLC d/b/a JP Labs is not a compounding pharmacy or outsourcing facility as defined under Sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.